Project lead at IMP (PI: Wolf B. Frommer)
We are interested in the bacterial leaf blight (BB) disease of rice caused by Xanthomonas oryzae pv. oryzae (Xoo). The postulate is that a pathogen infects a host to multiply. For bacterial or fungal pathogens this means in fine nutrition. Thus, a very fundamental question is how pathogens feed in the host. If we understand this, we understand the basements of host-pathogen systems. The analogy with thieves is very powerful since the same needs are driving both. On one hand, there is a need to get valuable goods (such as expensive items from a house owner or sucrose from the host plant) and on the other hand, there is the need to not be seen (by the alarm system for the thieves or the defense system for the plant-pathogens). Is there something more challenging than to look at someone or something that wishes to stay hidden?
Publications:
Differential regulation of glucose transport activity in yeast by specific cAMP signatures.
Clara Bermejo, Farzad Haerizadeh, Mayuri Sadoine, Diane Chermak, Wolf B. Frommer. Biochemical Journal, Portland Press Ltd., 2013, pp. 489—497
Affinity Purification of GO-Matryoshka Biosensors from E. coli for Quantitative Ratiometric Fluorescence Analyses.
Mayuri Sadoine$, Vanessa Castro-Rodriguez, Tobias Poloczek, Helene Javot, Erdem Sunal, Michael M Wudick, Wolf B Frommer. Bio-protocol, 2020, pp. e3773--e3773 ($corresponding author)
Affinity Series of Genetically Encoded Förster Resonance Energy-Transfer Sensors for Sucrose.
Mayuri Sadoine, Mira Reger, Ka Man Wong, Wolf B Frommer. ACS sensors, ACS Publications, 2021
Designs, applications, and limitations of genetically encoded fluorescent sensors to explore plant biology.
Mayuri Sadoine, Yuuma Ishikawa, Thomas J Kleist, Michael M Wudick, Masayoshi Nakamura, Guido Grossmann, Wolf B Frommer, Cheng-Hsun Ho. Plant Physiology, Oxford Academic Journals, 2021
Sucrose-dependence of sugar uptake, quorum sensing and virulence of the rice blight pathogen Xanthomonas oryzae pv. oryzae.
Mayuri Sadoine*, Juying Long*, Congfeng Song*, Yugander Arra, Wolf B Frommer, Bing Yang. bioRxiv, Cold Spring Harbor Laboratory, 2021 (in revision)
Role of a dual targeted sucrase and hexose transporters for virulence of the rice blight pathogen Xanthomonas oryzae pv. oryzae.
Mayuri Sadoine, Nora Zoellner, Yugander Arra, Erdem Sunal, Wolf B. Frommer (in preparation).
We are interested in the bacterial leaf blight (BB) disease of rice caused by Xanthomonas oryzae pv. oryzae (Xoo). The postulate is that a pathogen infects a host to multiply. For bacterial or fungal pathogens this means in fine nutrition. Thus, a very fundamental question is how pathogens feed in the host. If we understand this, we understand the basements of host-pathogen systems. The analogy with thieves is very powerful since the same needs are driving both. On one hand, there is a need to get valuable goods (such as expensive items from a house owner or sucrose from the host plant) and on the other hand, there is the need to not be seen (by the alarm system for the thieves or the defense system for the plant-pathogens). Is there something more challenging than to look at someone or something that wishes to stay hidden?
Publications:
Differential regulation of glucose transport activity in yeast by specific cAMP signatures.
Clara Bermejo, Farzad Haerizadeh, Mayuri Sadoine, Diane Chermak, Wolf B. Frommer. Biochemical Journal, Portland Press Ltd., 2013, pp. 489—497
Affinity Purification of GO-Matryoshka Biosensors from E. coli for Quantitative Ratiometric Fluorescence Analyses.
Mayuri Sadoine$, Vanessa Castro-Rodriguez, Tobias Poloczek, Helene Javot, Erdem Sunal, Michael M Wudick, Wolf B Frommer. Bio-protocol, 2020, pp. e3773--e3773 ($corresponding author)
Affinity Series of Genetically Encoded Förster Resonance Energy-Transfer Sensors for Sucrose.
Mayuri Sadoine, Mira Reger, Ka Man Wong, Wolf B Frommer. ACS sensors, ACS Publications, 2021
Designs, applications, and limitations of genetically encoded fluorescent sensors to explore plant biology.
Mayuri Sadoine, Yuuma Ishikawa, Thomas J Kleist, Michael M Wudick, Masayoshi Nakamura, Guido Grossmann, Wolf B Frommer, Cheng-Hsun Ho. Plant Physiology, Oxford Academic Journals, 2021
Sucrose-dependence of sugar uptake, quorum sensing and virulence of the rice blight pathogen Xanthomonas oryzae pv. oryzae.
Mayuri Sadoine*, Juying Long*, Congfeng Song*, Yugander Arra, Wolf B Frommer, Bing Yang. bioRxiv, Cold Spring Harbor Laboratory, 2021 (in revision)
Role of a dual targeted sucrase and hexose transporters for virulence of the rice blight pathogen Xanthomonas oryzae pv. oryzae.
Mayuri Sadoine, Nora Zoellner, Yugander Arra, Erdem Sunal, Wolf B. Frommer (in preparation).
